January 20, 2022

The World Live Breaking News Coverage & Updates IN ENGLISH

The World Live Breaking News Coverage & Updates IN ENGLISH

Covaxin booster effectively neutralises Omicron & Delta variants, shows Emory University study

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Covaxin booster effectively neutralises Omicron & Delta variants, shows Emory University study
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Covaxin booster effectively neutralises Omicron & Delta variants, shows Emory University study
Covaxin booster effectively neutralises Omicron & Delta variants, shows Emory University study

HYDERABAD: A booster shot of indigenously developed Covid-19 vaccine Covaxin, administered six months after getting two doses of the vaccine, has been found to successfully neutralise both the Omicron and Delta variants of SARS-CoV-2, a study conducted at Emory University has shown.
Bharat Biotech said the study conducted using a live virus neutralisation assay showed the booster dose generated robust neutralizing antibody responses against both Omicron (B.1.529) and Delta (B.1.617.2).
“100% of test serum samples showed neutralization of the Delta variant and more than 90% of serum samples showed neutralization of the Omicron variant,” Bharat Biotech said, pointing out that these data add to the body of evidence that the broad-spectrum mechanism of action of a whole virus inactivated Covid-19 vaccine like Covaxin is a viable option in this continuously evolving pandemic.
Bharat Biotech said the neutralization activity of Covaxin-boosted sera was comparable to what has been observed in mRNA vaccine-boosted sera against the Omicron variant with more than 90% of all individuals boosted with Covaxin showing neutralising antibodies.
“As the dominant Covid-19 variant throughout the world, Omicron poses a serious public health concern,” said Mehul Suthar, assistant professor, Emory Vaccine Center, who led the laboratory analysis.
“Data from this preliminary analysis show individuals receiving a booster dose of Covaxin have a significant immune response to both the Omicron and Delta variants. These findings suggest that a booster dose has the potential to reduce disease severity and hospitalizations,” Suthar added.
The study will be published on the pre-print server, medRXiv, shortly.
Bharat Biotech chairman & managing director Dr Krishna Ella said the company is in a continuous state of innovation and product development for Covaxin.
“The positive neutralization responses against the Omicron and Delta variants, validates our hypothesis of a multi-epitope vaccine generating both humoral and cell mediated immune responses. Our goals of developing a global vaccine against Covid-19 have been achieved with the use of Covaxin as a universal vaccine for adults and children,” he added.

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